Breaking down resistance
نویسندگان
چکیده
منابع مشابه
Breaking Down Insulin Resistance
The hormone insulin is critical for maintaining metabolic balance in the body. For example, skeletal muscle cells can’t take up glucose on their own, and require insulin exposure to spur uptake and use of glucose. Meanwhile, the action of insulin promotes storage of fat in white adipose tissue (WAT), forcing skeletal muscle to rely on glucose for fuel, and also preventing liver cells from relea...
متن کاملBreaking Down Resistance
Years of efforts have been invested in developing targeted cancer therapies by identifying the unique features of cancer cells and designing specific molecules to eliminate them while sparing their healthy neighbors. Spurred on by the initial success of imatinib mesylate in treating Philadelphia chromosome-positive leukemia, the emergence of resistance to targeted therapies caught many off guar...
متن کاملBreaking down online teaching: Innovation and resistance
The term “innovation” is associated mainly with change in practice using educational technology. This paper explores the question of why innovations in online teaching and learning in higher education break down or deliver less than they promise: why they are so resource intensive, so prone to breakdown, and why they often fail to live up to their promises? Two cases of innovation were selected...
متن کاملBreaking It Down :
s have been grouped by subject. The following table of contents outlines these subject groupings and provides direct links to the included abstracts within each group. If there are other subjects you would like to see the CJLS abstracting service include, please contact us at [email protected]. Table of
متن کاملBreaking down barriers
entrosomes are required for cytokinesis and are important in cell cycle progression—but how are centrosomes connected to these essential cellular functions at the molecular level? On page 535, Gromley et al. describe the maternal cen-triole protein centriolin, the first integral centrosome protein linked to both cytokinesis and cell cycle progression in vertebrate cells. Overexpression, siRNA s...
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ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2003
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc1081